l6 rat skeletal muscle myoblast cell line  (ATCC)

Journal: Biomedical Reports

Article Title: Biochanin‑A as SIRT‑1 modulator in preventing statin‑associated diabetogenesis: An in vitro study

doi: 10.3892/br.2025.1969

Figure Lengend Snippet: BA promotes the proliferation of L6 and MIN-6 cells. (A) L6 Cells were treated with varying concentrations of Atorvastatin to determine the IC 50 and the cell proliferation with the combination of Atorvastatin and BA by SRB assay. The value is represented as the mean ± SEM (n=3). (B) MIN-6 Cells were treated with BA against Atorvastatin-induced cytotoxicity. IC 50 of BA and Atorvastatin was analyzed. The highest cell proliferation was observed for the combination of Atorvastatin with 50 and 100 µM BA. The value is presented as the mean ± SEM (n=3). BA, Biochanin-A; SRB, sulforhodamine B.

Article Snippet: The mouse pancreatic beta cell line (MIN-6) and rat myoblast (L6) cell lines were procured from the American Type Culture Collection (ATCC).

Techniques: Sulforhodamine B Assay

Journal: Biomedicines

Article Title: Enhancing Mitochondrial Function Through Pharmacological Modification: A Novel Approach to Mitochondrial Transplantation in a Sepsis Model

doi: 10.3390/biomedicines13040934

Figure Lengend Snippet: Screening for candidate drugs to enhance mitochondrial function. The OCR was measured in L6 cells following treatment with six different drugs: ( a ) 30 nM formoterol; ( b ) bar graphs showing basal respiration, ATP production, maximal respiration, spare respiratory capacity, proton leak, and non-mitochondrial oxygen consumption; ( c ) 10 nM CoQ10; ( d ) 500 nM elamipretide; ( e ) 1 mM metformin; ( f ) 100 µM fenofibrate; and ( g ) 1 µM pioglitazone. The data are presented as the mean ± SD.

Article Snippet: The rat myoblast L6 cell line was purchased from ATCC (CRL-1458, Manassas, VA, USA).

Techniques: